Mesenchymal stromal cells
Ex vivo expansion of bone marrow, adipose and umbilical-derived MSCs with preserved tri-lineage potential.
Pooled hPL from 200+ AABB-approved U.S. donors. Heparin-free, xeno-free, fibrinogen-depleted — and a proven replacement for FBS in MSC, CAR-T, NK and stem cell expansion.
Human platelet lysate (hPL) is the cell culture supplement that finally delivers what fetal bovine serum can't: human-derived signaling, regulatory clarity, and consistent batch behavior — at concentrations as low as 2%.
Human platelets play an essential role in wound healing, tissue repair, inflammation, immunity and angiogenesis. When carefully lysed, their granules release a dense cocktail of growth factors, cytokines, adhesion molecules and bioavailable vitamins — exactly the signaling environment human cells expect.
Elk's pooled hPL is manufactured from FDA/AABB-approved apheresis platelet units, pooled across 200+ U.S. donors to minimize lot-to-lot variability. It is fibrinogen-depleted, so no heparin is required for use, and supplied with a Certificate of Analysis on every order.
Researchers see faster doubling times, lower supplement concentration, and a regulatory path that fetal bovine serum simply cannot offer.
Why teams developing MSC, CAR-T and stem-cell therapies are migrating off animal-derived serum. Lower concentration, human origin, regulatory documentation — and a more reliable supply.
| Parameter | Elk Pooled hPL | Fetal Bovine Serum (FBS) | Human AB Serum |
|---|---|---|---|
| Origin | 100% Human, pooled (200+ donors) | Bovine fetus | Human (single donor lots) |
| Xeno-free | ✓ Yes | ✗ No | ✓ Yes |
| GMP / FDA DMF | ✓ Both available | Varies by supplier | Varies by supplier |
| Typical use concentration | 2–10% | 10–20% | 5–10% |
| Bovine pathogen / prion risk | None | Documented risk | None |
| Lot-to-lot variability | Minimized (pooled) | High | High (single donor) |
| Heparin required | No (fibrinogen depleted) | — | Often required |
| Cost-effectiveness at scale | High | Moderate | Low |
| Clinical trial use | Worldwide | Limited (regulatory friction) | Limited supply |
Want the full technical comparison and protocol data? Request the spec sheet →
Every parameter — from donor sourcing to bottle format — is engineered for teams scaling from research to clinical manufacturing. Not a generic supplement repackaged.
Manufactured under GMP with an FDA Drug Master File on record — referenceable in your IND, ready for clinical translation.
200+ U.S. donors pooled per lot reduces variability that would otherwise compromise your assay reproducibility.
Higher doubling rates and improved viability for MSCs, CAR-T, NK and primary human cells — at 2–10% supplementation.
Our process removes fibrinogen — no clotting, no heparin supplementation, no extra optimization steps in your workflow.
Bottles for manufacturing protocols (25 / 100 / 250 / 500 mL) and closed-system cryobags (250 / 500 mL) for bioreactors.
Established supply partnerships and stable pricing — so commercial-scale planning doesn't depend on guesswork.
Used by cell therapy developers, regenerative medicine labs and contract manufacturers across four continents — at every stage from discovery to commercial GMP.
Ex vivo expansion of bone marrow, adipose and umbilical-derived MSCs with preserved tri-lineage potential.
Robust expansion of T-cells and NK cells without xenogenic protein contamination — direct fit for autologous and allogeneic programs.
Sustains EC propagation for vascular research and tissue-engineering applications without bovine carryover.
Suitable for iPSC and stem cell programs where xeno-free, regulatory-compliant supplements are mandatory.
Two product lines, both manufactured to identical specifications. Choose by workflow — both ship with CoA and FDA DMF reference letter on request.
GMP-ready human platelet lysate in Nalgene bottles — optimized for incorporation into established manufacturing protocols and benchtop expansion.
GMP-ready cryobags for automated clinical protocols and large-scale bioreactor manufacturing. Designed for closed-system sterile transfer.
Tell us your application and we'll respond within one business day with pricing, lead time, and a Certificate of Analysis from the most recent lot.
If you need anything more technical — CoA, DMF reference letter, growth-factor profiles, donor screening details — just request it in the form above.
Get a quote or just a conversation with our scientific team. We respond within one business day.